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Results for 'Cancer'
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Gene sequencing: Sensitive software detects diversity
24 April 2013Research Highlights
A new computer program readily identifies rare mutations harbored within diverse populations of cancer cells and microorganisms
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Structural biology: Characterizing a cancer complex
12 September 2012Research Highlights
Revelation of the function of a protein complex that controls cell proliferation in fruit fly wings provides insights into tumor growth
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Fighting cancer cells by stealth
12 September 2012Features & Innovations
Through a combination of two powerful methodologies, researchers at the A*STAR Institute of Bioengineering and Nanotechnology drive forward promising developments for gene therapy
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Research Highlights
Fluorescent dyes with aggregation-induced emission provide new probes for cancer diagnosis and therapy
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Cancer biology: Dangerous remainders
04 July 2012Research Highlights
Primitive cell populations retained from early embryonic development could provide the seeds for precancerous growths
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Oncology: Understanding the culprit
20 June 2012Research Highlights
Study using a systems biology approach reveals how the transcription factor EVI1 contributes to cancer development and tumor invasion
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Molecular biology: Preventing cell division
20 June 2012Research Highlights
One of the enzymes known to regulate the cell cycle has now been shown to play a key role in mitosis
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Research Highlights
The identification of a molecular pathway essential for the development and maintenance of tumor-initiating cells may prove invaluable to cancer treatment
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Nanoengineering: Targeting cancer stem cells
23 May 2012Research Highlights
Patented droplet microarray technology allows medical researchers to come to grips with rare cells
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Cancer biology: The good, the bad and the ugly
11 April 2012Research Highlights
The interaction between good and malignant immune cells may promote blood cancer invasiveness and progression
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Stem cells: In search of risky rearrangements
28 March 2012Research Highlights
Embryonic stem cell researchers collaborate to uncover genomic changes that might favor cancerous growth
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Cancer biology: Bringing battlers to the tumor
14 March 2012Research Highlights
Chemotherapeutic drugs fight melanoma by attracting immune cells into tumors
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Cancer biology: Sabotaging cellular stability
29 February 2012Research Highlights
Viruses clear the way for cancer by promoting the destruction of cell adhesion regulators
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Medicinal chemistry: Natural therapy
29 February 2012Research Highlights
Researchers have synthesized a fungal metabolite and derivatives that inhibit crucial enzymes related to cancers
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Cancer biology: The two faces of a cancer signal
01 February 2012Research Highlights
A protein in breast cancer cells acts as a bidirectional switch to modulate inflammatory gene expression
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Hepatology: Surveying survival outcomes in liver cancer
01 February 2012Research Highlights
A new molecular test for predicting liver cancer survival rates could lead to the development of improved immunotherapies
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Cancer biology: Cause of dissemination
18 January 2012Research Highlights
Invading immune cells promote the growth and spread of primary tumors
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Photonics: Light-and-heat therapy
21 December 2011Research Highlights
Plasmonic nanocrosses that heat up when illuminated can be used to kill cancer
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Genomics: Malignant rearrangements
07 December 2011Research Highlights
DNA sequencing reveals how breast cancer cells rearrange their genome to create fusion genes for driving tumor development
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Genomics: Sorting through the damage
23 November 2011Research Highlights
A high-throughput sequencing strategy allows scientists to follow cancer’s trail of genomic destruction
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Dermatology: The twists and turns of tumor treatment
23 November 2011Research Highlights
A melanoma drug is linked to long-term changes in the tumor environment in a subset of tumors that respond effectively to the drug
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Cancer biology: Cooperative partners
09 November 2011Research Highlights
Structural analysis indicates how two different antibodies to a cancer-causing protein could work together to block its function
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Hepatology: Breaking into liver cancer
26 October 2011Research Highlights
Chronic hepatitis B virus enhances liver cancer susceptibility by blocking a key DNA repair enzyme
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Cancer biology: Aggravating tumor aggressiveness
12 October 2011Research Highlights
A protein secreted from breast cancer cells enhances the spread and survival of tumor cells
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Cancer biology: The origin of esophageal cancer
28 September 2011Research Highlights
A new model for the origin of Barrett’s esophagus could lead to improved early treatment of esophageal cancer
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Bioimaging: Raman probes for cancer diagnostics
17 August 2011Research Highlights
A combinatorial approach speeds up the discovery of highly sensitive probes for detecting cancer
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Medical genetics: More than skin deep
03 August 2011Research Highlights
Self-healing skin cancer and Loeys–Dietz syndrome are caused by mutations in the same gene
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Research Highlights
A newly identified molecular mechanism could lead to treatments to control cancer
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Cancer biology: The key to transformation
11 May 2011Research Highlights
The regulatory protein Wbp2 enhances the ability of the transcriptional co-activator TAZ to transform healthy cells into cancer cells
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Nanomedicine: Loading up a cure
11 May 2011Research Highlights
A new type of polymer forms highly stable micelles with exceptional loading capacity for the targeted delivery of anticancer drugs
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Biosensors: Hormonal attractions
16 March 2011Research Highlights
Ultrasmall silicon wires could detect subtle changes in estrogen receptor-binding DNA sequences that are implicated in breast cancer
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Oncology: A very early warning
24 November 2010Research Highlights
The human papillomavirus protein E2 may serve as a diagnostic marker for cervical intraepithelial neoplasia, the precursor stages of cervical cancer
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Proteomics: Manipulating the milieu
24 November 2010Research Highlights
Cancer cells secrete proteins that help them adapt to low-oxygen environments
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Medical genetics: Many a little makes a mickle
10 November 2010Research Highlights
Genetic variations related to estrogen production have a cumulative effect on breast and endometrial cancer risk
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Cell biology: Taking wraps off mammalian Rap1
10 November 2010Research Highlights
Mammalian Rap1 controls transcription through the regulation of NF-κB activity
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Oncology: A double whammy
27 October 2010Research Highlights
HPV18 puts women at a higher risk of developing cervical cancer because the virus converts a repressor of the cell cycle into an activator
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Microbiology: On the trail of bacterial saboteurs
29 September 2010Research Highlights
A previously unidentified bacterial protein variant gums up the gears of a last-resort cellular suicide mechanism
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Finding the best approach in cancer research
01 September 2010Features & Innovations
Cancer geneticists in Singapore seek clinical relevance in large-scale cancer genomics studies.
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Immunology: Directing the defenders and destroyers
18 August 2010Research Highlights
Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments
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Cancer biology: Thwarting a sneak attack
07 July 2010Research Highlights
Metastatic spread begins surprisingly early in cancer but immune cells help keep it at bay
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Cancer: Fine-tuning cellular suicide
23 June 2010Research Highlights
Increasing the efficacy and minimizing unwanted side effects of cancer gene therapy has been made possible using a new approach
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Evolutionary genetics: Keeping cancer at bay
12 May 2010Research Highlights
Analysis of the genome of a primitive seafloor dweller shows that a well-known system for controlling DNA damage is highly conserved evolutionarily
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Cell biology: Helping receptors arrange transportation
03 February 2010Research Highlights
A previously uncharacterized cellular transport mechanism controls activity of a receptor involved in various cancers
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Cancer biology: Protein stability’s dark side
03 February 2010Research Highlights
Stabilization of a tumor-inducing protein by the human papillomavirus protein E2 may be an early step in cervical tumor formation
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Cancer biology: Finding patterns in repetition
20 January 2010Research Highlights
A sophisticated algorithm combines expression data with information about patient outcomes to reveal cancer genes
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Cancer biology: Breaking the cycle
06 January 2010Research Highlights
MicroRNA molecules represent an important regulatory roadblock preventing cancer cell proliferation
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Bioimaging: Keeping an eye on cancer
23 December 2009Research Highlights
Bioluminescence imaging allows real-time monitoring of cancer spreading through the body
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A protein witnessing 30 years of evolution in cancer research
23 December 2009Features & Innovations
Cancer-suppressor protein p53 has undergone dramatic shifts in understanding over the past 30 years, but now scientists are entering a new era in the development of novel p53-based therapies.
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Immunotherapy: Arming the body against liver cancer
11 November 2009Research Highlights
Immune cells that target tumors can be boosted in chronic hepatitis B sufferers
Recent Highlights
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Postdoctoral Research Fellow - Singapore Bioimaging Consortium (SBIC)
Bioimaging in fluorescence or PET/SPECT/MRI
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HPC Software Analyst @ A*STAR Computational Resource Centre (A*CRC)
Institute of High Performance Computing, Fusionopolis, Singapore
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