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Results for 'immunology'

  • Immunology: How one protein accelerates lupus

    13 March 2013

    Research Highlights

    A protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells

  • Immunology: Hepatitis B could be treatable in children

    27 February 2013

    Research Highlights

    Contrary to conventional wisdom, exposure to the hepatitis B virus activates immunity in young people, suggesting benefits for earlier treatment

  • Cerebral malaria: Pinpointing a potential therapeutic target

    16 January 2013

    Research Highlights

    Identification of the subtype of immune cells that is crucial to the onset of cerebral malaria provides a therapeutic starting point

  • Immunology: Matching mice and men

    24 October 2012

    Research Highlights

    Recently uncovered human counterparts to a subset of mouse immune cells may enable better vaccination strategies

  • Immunology: Losing ground to the enemy

    26 September 2012

    Research Highlights

    Inappropriate activation of an immune signaling pathway during infection leaves the body vulnerable to sepsis

  • Immunology: Jump-starting cheaper cancer vaccines

    26 September 2012

    Research Highlights

    A technique to prime stem cells to induce anti-tumor immunity may open the door to economical production of anticancer shots

  • Immunology: The kick-starters of immune cells

    12 September 2012

    Research Highlights

    Lipids produced within the thymus give immune cells the initial boost they need to fight off infection

  • Immunology: Vaccine hope for virile virus

    04 July 2012

    Research Highlights

    Exploiting the early immune response in Chikungunya fever promises to provide protection

  • Biological imaging: Skin deep

    20 June 2012

    Research Highlights

    A novel live-cell imaging technique offers new opportunities to understanding immune responses in the skin

  • Immunology: For one and for all

    06 June 2012

    Research Highlights

    The infection of one dengue virus subtype can lead to the production of antibodies that confer protection against other dengue virus subtypes

  • Immunology: Lose some, gain some

    23 May 2012

    Research Highlights

    Calicneurin inhibitors, used clinically as immunosuppressive drugs, are shown to confer a growth advantage to myeloid cells

  • Immunology: Guiding the immune response

    09 May 2012

    Research Highlights

    Uric acid released from dying cells is a key driver of autoimmune diseases

  • Cancer biology: The good, the bad and the ugly

    11 April 2012

    Research Highlights

    The interaction between good and malignant immune cells may promote blood cancer invasiveness and progression

  • Immunology: Monocytes are not all the same

    21 December 2011

    Research Highlights

    Understanding the differences between various monocyte subtypes could aid diagnosis of blood disorders

  • Immunology: Many ways to fight infection

    31 August 2011

    Research Highlights

    T cells use a multi-pronged approach to promote an inflammatory counterattack against infectious threats

  • Immunology: Learning through interaction

    17 August 2011

    Research Highlights

    Vaccine development could be aided by increased understanding of the physical interactions between immune cells

  • Immunology: Cooperating partners

    13 April 2011

    Research Highlights

    Three proteins work together to induce the production of an inflammatory factor in human immune cells

  • Immunology: A new weapon against Chikungunya

    16 March 2011

    Research Highlights

    Antibodies derived from an individual who had previously been exposed to the Chikungunya virus raise hope of a new therapy

  • Immunology: Cells on patrol

    02 March 2011

    Research Highlights

    A subset of human immune cells monitors blood vessels for viral infection

  • The digital side of biology

    02 March 2011

    Features & Innovations

    The rapid development of computational tools is shedding light on new genetic and molecular studies, but it is also creating headaches for the scientists involved in this research.

  • Immunology: Directing the defenders and destroyers

    18 August 2010

    Research Highlights

    Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments

  • A new initiative to curb tuberculosis

    18 August 2010

    Features & Innovations

    The Singapore Immunology Network has launched a US$2 million program to identify biomarkers for this ancient infectious disease.

  • Immunology: Viral hitchhiker

    21 July 2010

    Research Highlights

    Success in deciphering the mechanisms of infection and spread of Chikungunya virus within humans points the way to control strategies

  • Immunology: Signaling disease

    21 July 2010

    Research Highlights

    Individuals carrying variants of a gene involved in controlling the immune response are prone to infection

  • Tackling the ever-growing threat of dengue fever

    12 May 2010

    Features & Innovations

    Scientists at A*STAR are taking a diversified approach to combating dengue fever, an infectious tropical disease that is fast becoming a major global threat to health and the economy.

  • Dengue fever: Taming the virus

    03 March 2010

    Research Highlights

    Immune cells infected by the dengue virus play a key role in fighting against viral growth

  • Genetics: Invitations to infection

    03 March 2010

    Research Highlights

    Genomic analysis reveals risk factors that offer insights into the pathology of the leprosy bacterium

  • Malaria: A shot in the arm for treatment options

    03 February 2010

    Research Highlights

    A ‘whole parasite’ strategy could lead to a vaccine for one of the world’s deadliest diseases

  • Malaria: Hitting parasites where they hide

    03 February 2010

    Features & Innovations

    Drugs that selectively target pre-symptomatic, liver-stage malarial infection could ultimately help thwart this deadly disease.

  • Genetics: Following regulation to the letter

    06 January 2010

    Research Highlights

    Subtle sequence changes determine whether a common gene regulatory sequence acts as an ‘on’ or ‘off’ switch

  • Biochemistry: Finding the off switch

    23 December 2009

    Research Highlights

    Genetic evidence reveals that an enzyme that deactivates signaling pathways is associated with inflammation and cancer

  • Stem cells: Differentiate or die

    23 December 2009

    Research Highlights

    An antibody that selectively kills off undifferentiated stem cells may improve their clinical usefulness

  • Immunology: Standing out in a crowd

    09 December 2009

    Research Highlights

    Surface features enable efficient purification of cells that help thwart autoimmunity and prevent tissue graft rejection

Recent Highlights

  • Carbon capture: Making use of minerals
  • Optics: Statistics light the way
  • Plasmonics: A wave without diffraction
  • Genomics: A rare view of gene regulation

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