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Results for 'immunology'
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Immunology: How one protein accelerates lupus
13 March 2013Research Highlights
A protein implicated in lupus promotes disease progression by distinct mechanisms in different immune cells
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Immunology: Hepatitis B could be treatable in children
27 February 2013Research Highlights
Contrary to conventional wisdom, exposure to the hepatitis B virus activates immunity in young people, suggesting benefits for earlier treatment
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Cerebral malaria: Pinpointing a potential therapeutic target
16 January 2013Research Highlights
Identification of the subtype of immune cells that is crucial to the onset of cerebral malaria provides a therapeutic starting point
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Immunology: Matching mice and men
24 October 2012Research Highlights
Recently uncovered human counterparts to a subset of mouse immune cells may enable better vaccination strategies
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Immunology: Losing ground to the enemy
26 September 2012Research Highlights
Inappropriate activation of an immune signaling pathway during infection leaves the body vulnerable to sepsis
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Immunology: Jump-starting cheaper cancer vaccines
26 September 2012Research Highlights
A technique to prime stem cells to induce anti-tumor immunity may open the door to economical production of anticancer shots
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Immunology: The kick-starters of immune cells
12 September 2012Research Highlights
Lipids produced within the thymus give immune cells the initial boost they need to fight off infection
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Immunology: Vaccine hope for virile virus
04 July 2012Research Highlights
Exploiting the early immune response in Chikungunya fever promises to provide protection
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Biological imaging: Skin deep
20 June 2012Research Highlights
A novel live-cell imaging technique offers new opportunities to understanding immune responses in the skin
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Immunology: For one and for all
06 June 2012Research Highlights
The infection of one dengue virus subtype can lead to the production of antibodies that confer protection against other dengue virus subtypes
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Immunology: Lose some, gain some
23 May 2012Research Highlights
Calicneurin inhibitors, used clinically as immunosuppressive drugs, are shown to confer a growth advantage to myeloid cells
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Immunology: Guiding the immune response
09 May 2012Research Highlights
Uric acid released from dying cells is a key driver of autoimmune diseases
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Cancer biology: The good, the bad and the ugly
11 April 2012Research Highlights
The interaction between good and malignant immune cells may promote blood cancer invasiveness and progression
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Immunology: Monocytes are not all the same
21 December 2011Research Highlights
Understanding the differences between various monocyte subtypes could aid diagnosis of blood disorders
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Immunology: Many ways to fight infection
31 August 2011Research Highlights
T cells use a multi-pronged approach to promote an inflammatory counterattack against infectious threats
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Immunology: Learning through interaction
17 August 2011Research Highlights
Vaccine development could be aided by increased understanding of the physical interactions between immune cells
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Immunology: Cooperating partners
13 April 2011Research Highlights
Three proteins work together to induce the production of an inflammatory factor in human immune cells
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Immunology: A new weapon against Chikungunya
16 March 2011Research Highlights
Antibodies derived from an individual who had previously been exposed to the Chikungunya virus raise hope of a new therapy
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Immunology: Cells on patrol
02 March 2011Research Highlights
A subset of human immune cells monitors blood vessels for viral infection
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The digital side of biology
02 March 2011Features & Innovations
The rapid development of computational tools is shedding light on new genetic and molecular studies, but it is also creating headaches for the scientists involved in this research.
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Immunology: Directing the defenders and destroyers
18 August 2010Research Highlights
Identification of a previously unknown interaction between immune-system cells points the way to novel cancer treatments
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A new initiative to curb tuberculosis
18 August 2010Features & Innovations
The Singapore Immunology Network has launched a US$2 million program to identify biomarkers for this ancient infectious disease.
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Immunology: Viral hitchhiker
21 July 2010Research Highlights
Success in deciphering the mechanisms of infection and spread of Chikungunya virus within humans points the way to control strategies
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Immunology: Signaling disease
21 July 2010Research Highlights
Individuals carrying variants of a gene involved in controlling the immune response are prone to infection
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Tackling the ever-growing threat of dengue fever
12 May 2010Features & Innovations
Scientists at A*STAR are taking a diversified approach to combating dengue fever, an infectious tropical disease that is fast becoming a major global threat to health and the economy.
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Dengue fever: Taming the virus
03 March 2010Research Highlights
Immune cells infected by the dengue virus play a key role in fighting against viral growth
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Genetics: Invitations to infection
03 March 2010Research Highlights
Genomic analysis reveals risk factors that offer insights into the pathology of the leprosy bacterium
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Malaria: A shot in the arm for treatment options
03 February 2010Research Highlights
A ‘whole parasite’ strategy could lead to a vaccine for one of the world’s deadliest diseases
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Malaria: Hitting parasites where they hide
03 February 2010Features & Innovations
Drugs that selectively target pre-symptomatic, liver-stage malarial infection could ultimately help thwart this deadly disease.
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Genetics: Following regulation to the letter
06 January 2010Research Highlights
Subtle sequence changes determine whether a common gene regulatory sequence acts as an ‘on’ or ‘off’ switch
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Biochemistry: Finding the off switch
23 December 2009Research Highlights
Genetic evidence reveals that an enzyme that deactivates signaling pathways is associated with inflammation and cancer
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Stem cells: Differentiate or die
23 December 2009Research Highlights
An antibody that selectively kills off undifferentiated stem cells may improve their clinical usefulness
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Immunology: Standing out in a crowd
09 December 2009Research Highlights
Surface features enable efficient purification of cells that help thwart autoimmunity and prevent tissue graft rejection


