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Results for 'proteins'
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Biopurification: Convection trumps diffusion
22 May 2013Research Highlights
Breakthrough technology quickly separates large proteins and viruses from their surroundings, which improves purification of vaccines and protein therapuetics
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Structural biology: Characterizing a cancer complex
12 September 2012Research Highlights
Revelation of the function of a protein complex that controls cell proliferation in fruit fly wings provides insights into tumor growth
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Developmental biology: Off to a good start
01 August 2012Research Highlights
A protein thwarts developmental abnormalities by preventing removal of critical chemical marks from embryonic DNA
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Stem cells: Promoting difference
01 August 2012Research Highlights
Two proteins that regulate cell division co-operate to control neuronal differentiation
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Molecular biology: A subtle switch
15 February 2012Research Highlights
Small alterations to a chromosomal protein have far-reaching effects on gene expression activity
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Stem cells: Driving neuronal differentiation
07 December 2011Research Highlights
Identification of a signaling pathway could aid development of stem cell-based therapies for Parkinson’s disease
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Nanotechnology: Probing for interactions
23 November 2011Research Highlights
Nanoparticles offer insights into interactions between single-stranded DNA and their binding proteins
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Molecular genetics: A collective effort
09 November 2011Research Highlights
Gene regulation may depend more on the synergy of multiple proteins rather than discrete contributions of individual factors
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Cancer biology: Aggravating tumor aggressiveness
12 October 2011Research Highlights
A protein secreted from breast cancer cells enhances the spread and survival of tumor cells
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Cell biology: Following the toxin trails
12 October 2011Research Highlights
Clarifying how deadly protein toxins hijack cellular processes to enter human cells will help in the development of antidotes
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Cell biology: Many ways to reach out
20 July 2011Research Highlights
Time-lapse imaging reveals how cells get a feel for their environment
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Immunology: Getting into shape
22 June 2011Research Highlights
Structural analysis of the interaction between human leukocyte antigens and hepatitis B viruses reveals a path to better vaccine design
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Bioimaging: Different places, different rules
08 June 2011Research Highlights
Small molecules that bind one protein inside the test tube may or may not bind the same protein inside the living cell
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Cancer biology: The key to transformation
11 May 2011Research Highlights
The regulatory protein Wbp2 enhances the ability of the transcriptional co-activator TAZ to transform healthy cells into cancer cells
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Research Highlights
Efforts to understand a signaling factor’s contradictory behavior reveal a master switch for organ development
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Immunology: Cooperating partners
13 April 2011Research Highlights
Three proteins work together to induce the production of an inflammatory factor in human immune cells
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Metabolic engineering: Hamster rules
02 March 2011Research Highlights
Chinese hamster ovary and baby hamster kidney cell lines are the best choices for producing therapeutic glycoprotein that stays in the bloodstream longer
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Cell biology: A new player in protein secretion
10 November 2010Research Highlights
Scientists are establishing the basic molecular network of a new player involved in protein secretion and clarifying its regulation in mammalian cells
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Cell biology: Taking wraps off mammalian Rap1
10 November 2010Research Highlights
Mammalian Rap1 controls transcription through the regulation of NF-κB activity
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Metabolism: Another way to keep thin?
13 October 2010Research Highlights
A highly truncated receptor protein variant retains the ability to modulate metabolic activity in mice
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Biochemistry: Out of the loop
29 September 2010Research Highlights
Molecular dynamics simulations show why scientists have failed to generate an active form of the protein kinase PAK1
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Cancer biology: Regulatory dysfunction spells trouble
29 September 2010Research Highlights
Discovery of the mechanism regulating the expression of an enzyme implicated in human cancer could open new avenues for treatment
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Cancer biology: Finding the right fit
21 July 2010Research Highlights
A molecular library yields a promising candidate for thwarting the ability of cancer cells to elude chemotherapy
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Structural biology: Many ways to form a filament
12 May 2010Research Highlights
The proteins that provide essential infrastructure for bacteria exhibit remarkable diversity of structure and function
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Cell biology: Stopping bad news from spreading
31 March 2010Research Highlights
Dividing cells employ multiple, parallel countermeasures to prevent the transmission of damaged genetic material
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Structural biology: Little triggers, big changes
17 March 2010Research Highlights
Two calcium-binding events set major structural rearrangements into motion for an important regulatory protein of human cells
Recent Highlights
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Postdoctoral Research Fellow - Singapore Bioimaging Consortium (SBIC)
Bioimaging in fluorescence or PET/SPECT/MRI
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HPC Software Analyst @ A*STAR Computational Resource Centre (A*CRC)
Institute of High Performance Computing, Fusionopolis, Singapore
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