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Results for 'stem cells'

  • Understanding the individual

    22 May 2013

    Features & Innovations

    A*STAR’s Single-Cell Omics Centre, the first research center in Asia exclusively dedicated to accelerating the understanding of how individual cells work, officially opened in April 2013

  • Stem cells: Keeping differentiation in check

    27 February 2013

    Research Highlights

    A repressor protein that blocks differentiation-specific genes helps maintain stem cells' ability to develop into any cell type

  • Stem cells: Laboratory bioreactor boosts yields

    05 December 2012

    Research Highlights

    Inducing stem cells to become different cell types efficiently, and on a large scale, is now possible using a three-dimensional platform

  • Developmental biology: Foundations for a filter

    07 November 2012

    Research Highlights

    A recently discovered stem cell population could one day provide useful source material for kidney repair

  • Biomaterials: Building up stem cell production

    26 September 2012

    Research Highlights

    A three-dimensional fiber scaffold promotes large-scale stem cell proliferation and differentiation to levels suitable for tissue transplants

  • Immunology: Jump-starting cheaper cancer vaccines

    26 September 2012

    Research Highlights

    A technique to prime stem cells to induce anti-tumor immunity may open the door to economical production of anticancer shots

  • Immunology: Lose some, gain some

    23 May 2012

    Research Highlights

    Calicneurin inhibitors, used clinically as immunosuppressive drugs, are shown to confer a growth advantage to myeloid cells

  • Strengthening stem cell research

    23 May 2012

    Features & Innovations

    Remarkable strides are being made in stem cell research at the A*STAR Institute of Bioengineering and Nanotechnology, leading to the development of novel therapeutic and diagnostic strategies

  • Developmental biology: Switching to neurons

    09 May 2012

    Research Highlights

    Researchers identify a genetic switch that controls differentiation of embryonic stem cells into neural cells

  • Stem cells: In search of risky rearrangements

    28 March 2012

    Research Highlights

    Embryonic stem cell researchers collaborate to uncover genomic changes that might favor cancerous growth

  • Bioengineering: Heart-to-heart

    29 February 2012

    Research Highlights

    Stem cells grown on a scaffold form new heart tissues and may lead to the creation of functioning bioartificial hearts

  • Stem cells: A new breath of life

    18 January 2012

    Research Highlights

    The discovery of distal airway stem cells opens the door to new therapies for reversing pulmonary disease

  • Immunology: A big role for small RNAs

    18 January 2012

    Research Highlights

    MicroRNAs are essential for B-cell development and antibody production

  • Stem cells: Driving neuronal differentiation

    07 December 2011

    Research Highlights

    Identification of a signaling pathway could aid development of stem cell-based therapies for Parkinson’s disease

  • Stem cells: Knowing what they want to be in life

    07 December 2011

    Research Highlights

    Collaborative study sheds light on our understanding of how stem cells differentiate during embryonic development

  • Stem cells: Battle of the sex chromosomes

    26 October 2011

    Research Highlights

    Skewed X chromosome expression may confound laboratory models of human diseases

  • Stem cells: A way to maintain pluripotency

    12 October 2011

    Research Highlights

    Fibroblast growth factor-2 keeps stems cells in their undifferentiated state by activating Wnt signaling

  • Cancer biology: The origin of esophageal cancer

    28 September 2011

    Research Highlights

    A new model for the origin of Barrett’s esophagus could lead to improved early treatment of esophageal cancer

  • Stem cells: Differentiation in the balance

    14 September 2011

    Research Highlights

    The differentiation of stem cells into particular fetal cell lineages is a precarious affair acted out on a molecular battlefield

  • Proteomics: Stem cell signaling

    31 August 2011

    Research Highlights

    Tyrosine phosphorylation profiles illuminate the molecular basis of self-renewal in human embryonic stem cells

  • Stem cells: Reprogramming with synthetic proteins

    06 July 2011

    Research Highlights

    Genetically engineered proteins can be used to revert cells back to their undifferentiated state

  • Developmental biology: Inside the decision-making process

    27 April 2011

    Research Highlights

    Efforts to understand a signaling factor’s contradictory behavior reveal a master switch for organ development

  • Molecular biology: Go back in time

    16 March 2011

    Research Highlights

    Stem-cell technology can help reveal the pathology of a wide range of genetic diseases, including progeria

  • Stem cells: Essential factors

    02 March 2011

    Research Highlights

    A genome-wide RNA interference screen identifies genes that govern the unique properties of human embryonic stem cells

  • Biomaterials: Finding the right support

    19 January 2011

    Research Highlights

    Scaffolds that are able to support stem-cell proliferation and differentiation in culture may not have the same effects in the human body

  • Biomaterials: The right gel for the right cell

    22 December 2010

    Research Highlights

    It is possible to control the differentiation of stem cells by changing the stiffness of a hydrogel

  • Stem cells: Brighten up

    10 November 2010

    Research Highlights

    A fluorescent probe that selectively highlights embryonic and induced pluripotent stem cells is now available

  • The landscape of stem-cell research

    13 October 2010

    Features & Innovations

    Stem-cell research is diversifying more than ever in Singapore.

  • Bioprocess engineering: Healing a broken heart

    13 October 2010

    Research Highlights

    A new bioprocessing system enables large-scale production of heart muscle cells from stem cells

  • Stem cells: Driving differentiation

    15 September 2010

    Research Highlights

    Mysterious molecules called lncRNA direct the fate of stem cells in the early mouse embryo

  • Stem cells: Eliminating the enemy within

    26 May 2010

    Research Highlights

    An evaluation study shows that more efficient cell-sorting methods are needed to make stem cell-derived tissues sufficiently safe for transplantation

  • Stem cells: Expanding the repertoire

    28 April 2010

    Research Highlights

    Discovery of a replacement for an ‘indispensible’ reprogramming factor provides new ways to generate stem cells

  • Stem cells: Quality improvement

    31 March 2010

    Research Highlights

    Reprogrammed adult cells can display different qualities depending on how they were generated

  • Biomaterials: Liver repairs

    17 March 2010

    Research Highlights

    A fibrous polymer scaffold can deliver liver-like cells into damaged liver for tissue repair

  • Stem cells: Differentiate or die

    23 December 2009

    Research Highlights

    An antibody that selectively kills off undifferentiated stem cells may improve their clinical usefulness

  • Stem cells: A new part of the program

    11 November 2009

    Research Highlights

    A novel transcription factor can facilitate the reprogramming of somatic cells into stem cells

  • Stem cells: Maintaining ‘arrested development’

    11 November 2009

    Research Highlights

    Embryonic stem cells keep their developmental options open with help from two recently identified genes

Recent Highlights

  • Organic electronics: A faster way to move electrons
  • Data storage: Making the switch
  • Developmental biology: Proteins prove the power of collaboration
  • Hybrid nanostructures: Getting to the core

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