Cancer

Features and Innovations

Turning up the heat on hydrogels

04 February 15

Researchers at A*STAR have developed temperature-sensitive gels that can be used for a wide range of biomedical and cosmetic applications

Biopolis: Ten years on

20 November 13

A decade after the opening of Biopolis, Singapore’s premier biomedical sciences research hub, A*STAR’s multifaceted activities are spurring discovery and innovation with a global reach

Fighting cancer cells by stealth

12 September 12

Through a combination of two powerful methodologies, researchers at the A*STAR Institute of Bioengineering and Nanotechnology drive forward promising developments for gene therapy

Research Highlights

Biosensors: A light diagnosis

09 March 16

On-the-spot diagnosis of certain cancers and other diseases is closer to becoming a reality thanks to a sensitive biosensor

Cancer biology: Tumor-causing crosstalk

03 December 14

Signals that pass between genetically abnormal epithelial cells and their genetically normal support cells drive tumor formation in a fruit fly cancer model

Cancer biology: Keeping bad company

16 January 13

Certain mutations cause a cancer-preventing protein to interfere with cellular pathways and actively drive cancer progression 

Oncology: Understanding the culprit

20 June 12

Study using a systems biology approach reveals how the transcription factor EVI1 contributes to cancer development and tumor invasion

Genomics: Malignant rearrangements

07 December 11

DNA sequencing reveals how breast cancer cells rearrange their genome to create fusion genes for driving tumor development

Cancer biology: Cooperative partners

09 November 11

Structural analysis indicates how two different antibodies to a cancer-causing protein could work together to block its function

Nanomedicine: Loading up a cure

11 May 11

A new type of polymer forms highly stable micelles with exceptional loading capacity for the targeted delivery of anticancer drugs

Biosensors: Hormonal attractions

16 March 11

Ultrasmall silicon wires could detect subtle changes in estrogen receptor-binding DNA sequences that are implicated in breast cancer

Oncology: A very early warning

24 November 10

The human papillomavirus protein E2 may serve as a diagnostic marker for cervical intraepithelial neoplasia, the precursor stages of cervical cancer

Oncology: A double whammy

27 October 10

HPV18 puts women at a higher risk of developing cervical cancer because the virus converts a repressor of the cell cycle into an activator